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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
15.45
Human Site:
S1758
Identified Species:
28.33
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S1758
Q
Q
A
S
A
S
S
S
A
P
N
K
N
Q
L
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S1758
Q
Q
A
S
A
S
S
S
A
P
N
K
N
Q
L
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
W1235
A
S
Q
F
S
L
Q
W
E
S
Y
V
K
R
F
Dog
Lupus familis
XP_536285
2273
247246
V1205
K
K
K
P
T
S
P
V
K
P
I
P
Q
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
S1756
Q
Q
A
S
S
T
S
S
G
A
N
K
N
Q
V
Rat
Rattus norvegicus
P70478
2842
310514
S1756
Q
Q
A
S
M
T
S
S
G
T
N
K
N
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S1763
Q
Q
A
S
A
A
S
S
G
S
S
I
S
Q
P
Chicken
Gallus gallus
XP_001233411
2232
244958
E1164
D
S
V
G
A
G
A
E
S
G
E
F
E
K
R
Frog
Xenopus laevis
P70039
2829
310863
A1756
Q
I
N
H
T
S
A
A
T
S
S
G
N
S
R
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
L1673
A
E
A
K
E
T
G
L
S
P
P
M
Q
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
F1349
R
P
K
S
N
L
G
F
S
S
N
G
K
R
S
Honey Bee
Apis mellifera
XP_624558
2760
306907
I1691
N
S
A
S
L
P
P
I
Q
V
K
N
V
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
A2090
P
R
I
T
K
P
S
A
S
V
E
E
K
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
0
13.3
N.A.
66.6
66.6
N.A.
53.3
6.6
20
13.3
N.A.
13.3
20
N.A.
6.6
P-Site Similarity:
100
100
13.3
26.6
N.A.
86.6
80
N.A.
73.3
26.6
40
33.3
N.A.
33.3
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
54
0
31
8
16
16
16
8
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
0
8
8
0
16
8
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
8
% F
% Gly:
0
0
0
8
0
8
16
0
24
8
0
16
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
8
0
0
8
8
0
0
8
% I
% Lys:
8
8
16
8
8
0
0
0
8
0
8
31
24
8
0
% K
% Leu:
0
0
0
0
8
16
0
8
0
0
0
0
0
0
24
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
8
0
8
0
0
0
0
0
39
8
39
0
0
% N
% Pro:
8
8
0
8
0
16
16
0
0
31
8
8
0
0
8
% P
% Gln:
47
39
8
0
0
0
8
0
8
0
0
0
16
39
0
% Q
% Arg:
8
8
0
0
0
0
0
0
0
0
0
0
0
16
16
% R
% Ser:
0
24
0
54
16
31
47
39
31
31
16
0
8
39
8
% S
% Thr:
0
0
0
8
16
24
0
0
8
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
8
0
16
0
8
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _